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OCTOBER 10, 2017

Research Extras

 
Emory Medicine Magazine
Skin patches with dissolvable microneedles may be a future alternative to traditional flu shots and could significantly increase the number of people who get vaccinated. Emory principal investigator Nadine Rouphael shows how the small patch was applied to clinical trial volunteer Daisy Bourassa.

INFECTIOUS DISEASES
Microneedle patches for flu vaccination prove successful in first clinical trial
Adhesive skin patches containing dissolvable microscopic needles applied to the skin were found to be safe and well tolerated in a phase I clinical trial. The microneedle patches containing influenza vaccine were nearly painless to apply, were just as effective in generating immunity against the flu, and were strongly preferred over traditional flu shots. The microneedle patches could also save money because they are easily self-administered, could be transported and stored without refrigeration, and are easily disposed of after use without sharps waste. Emory and Georgia Tech researchers led the study, following years of research and development. Read more...


 
 
alzheimer;s
Both Alzheimer's and Parkinson's diseases include sticky proteins that damage brain cells.
NEUROSCIENCE
Alzheimer's and Parkinson's diseases may be spurred by same enzyme
Although Alzheimer's disease and Parkinson's diseases affect different regions of the brain and have distinct genetic and environmental risk factors, scientists have found similarities in an enzyme at the biochemical level that could lead to a potential drug target for Parkinson's. Read more...




elegans
Scientists believe indoles, found in many creatures, including this C. elegans worm, could be a direct avenue to helping people increase their '"healthspan."
MICROBIOME
Chemicals from intestinal bacteria maintain vitality in aging animals
A class of chemicals made by intestinal bacteria, known as indoles, help worms, flies and mice maintain mobility and resilience for more of their lifespans, scientists have discovered. These chemicals could be a clue to developing drugs that could also help humans live not necessarily longer, but healthier lives.  Read more...



fire ants
Solenopsins from fire ant venom could restore the skin's natural barrier without the toxic side effects of some current treatments.
DRUG DISCOVERY
Fire ant venom may lead to psoriasis treatment
Compounds in fire ant venom may be used to develop new treatments for psoriasis, a common autoimmune skin disease. Solenopsins, the main toxic component of fire ant venom, resemble ceramides — the chemicals present in current topical treatments for psoriasis — but they avoid the inflammatory problems ceramides sometimes create. Read more...




Editor, Holly Korschun, Executive Director of Research Communications
Managing Editor, David S. Stephens, MD, Vice President for Research