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JANUARY 9, 2015

Research Extras

A lengthy journey through the research and development pipeline ends successfully for an Emory-developed hemophilia drug

Emory-Developed Drug Approved for Acquired Hemophilia
Obizur, a drug for acquired hemophilia A originally developed by a team of Emory hematologists, has been approved by the FDA. The technology first licensed from Emory in 1998 was brought to market in fall 2014 by Baxter International. Read more...

Stroke victims could potentially get long-term help from a relative of the clot buster tPA.
Clot Buster's Tardy Twin Could Aid in Stroke Recovery
A protein called uPA could help neurons recover beyond the early hours after an acute stroke, when doctors often work to dissolve a blood clot with the drug tPA. uPA has been tested in the lab and in some countries in stroke treatment. Released over several hours, it could help brain cells recover from injuries caused by the loss of blood flow. Read more...

Sorted bone marrow cells, when used in large enough quantities, are helping some patients heal after heart attack.
More Cells = Better Outcomes in Cell Therapy for Heart Attack
In a clinical trial using patients' own bone marrow cells to improve recovery after heart attack, patients who received more of the sorted cells, called endothelial progenitor cells, had fewer adverse cardiac events and more positive cardiac markers. With this new knowledge, researchers will conduct studies to refine use of the higher cell dosage. Read more...

Maintaining proper balance among the nearly 1,000 microorganisms in the intestine is essential for human health.
Fecal Transplants Heal Intestinal Infections by Upping Microbial Diversity
Frequent antibiotics can wipe out beneficial intestinal microbes, leading to chronic, drug- resistant diarrheal infections like C. difficile. Fecal transplants are proving effective in restoring intestinal balance and improving health. Researchers are studying the gut microbiome after fecal transplants to measure the precise effects leading to recovery. Read more...

Editor, Holly Korschun, Director of Research Communications
Managing Editor, David S. Stephens, MD, Vice President for Research