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FEBRUARY 27, 2015

Research Extras

 
Distinct immune responses to Mycobacterium tuberculosis create varying risks for latent and active disease, giving researchers a basis for better prevention and treatment.

INFECTIOUS DISEASES
NIH Partnership Aims to Stop Tuberculosis by Unraveling Immune Responses in Latent and Active Cases
About one third of the world's population carries latent TB, but scientists don't really understand why some cases progress to active disease. Emory researchers leading a new seven-year, NIH-funded partnership believe differences in disease responses correspond to varying levels of antigen-specific T cell responses. By learning more, they hope to improve diagnosis, prevention, vaccines, and therapies. Read more...


 
 
More premature infants survive thanks to improved interventions, but prevention of prematurity is still critical.
PEDIATRICS
Survival of Premature Infants Increases, with Fewer Dying of Lung Problems
A decade of data shows an increase in survival among very premature infants because of improvements in prenatal and postnatal care. Even better strategies are needed to prevent extreme prematurity and to improve long-term infant health. One in four extremely premature infants still does not survive the birth hospitalization. Read more...



In the ongoing debate about dietary sodium, not much has been known about salt intake in older adults, especially those with normal blood pressure.
CARDIOLOGY
Salt Intake Among Older Americans Not Linked to Heart Disease or Death
A study based on self-reported information from adults ages 71 to 80 found salt intake was not associated with mortality or new risk for cardiovascular disease. The follow-up data came 10 years after an NIH baseline study on aging. The results don't apply to those with pre-existing heart disease and are not a "license" to consume more salt, say researchers. Read more...



A vaccine that targets the parts of the virus responsible for replication could have a significant impact on HIV.
INFECTIOUS DISEASES
Rapidly Replicating HIV Strains Drive Inflammation and Disease Progression
The particular strain of HIV someone is infected with and its ability to quickly replicate in the body has a lasting impact on immune response and disease outcome. People infected with a highly replicative HIV strain show more signs of early acute inflammation and immune cell "exhaustion" and faster disease progression. Read more...



Editor, Holly Korschun, Executive Director of Research Communications
Managing Editor, David S. Stephens, MD, Vice President for Research