Emory Researchers Seek
Participants for Study Examining Effects of Fat Intake on Blood Vessel
Researchers at Emory University and the Atlanta VA Medical Center are
conducting a study to determine how fat intake effects blood vessel
wall elasticity and inflammation. Men over the age of 40 and women over
50 are needed.
Volunteer participants must
have high cholesterol, must not be taking any cholesterol-lowering drugs
for the past three months, and must have a history of heart disease
or high risk for heart disease (diabetes, smoking, hypertension or peripheral
Participants will be given
varied doses of polyunsaturated fats in the form of a shake or capsules,
have their blood drawn and have a non-invasive test using blood pressure
cuffs to measure blood vessel compliance, function and health.
Researchers will measure
the effect that fat dosages have on vessel elasticity or compliance
as well as endothelial function. They will also measure markers of inflammation
in their blood to see if these areas are effected by the fat meal. Subsequently,
the researchers will compare the difference in these effects caused
by different doses and types of polyunsaturated fatty acids.
The study requires a routine
office visit, then four office visits over a four-week period, each
lasting approximately four hours.
The principal investigator
is Virgil Brown, M.D, Charles Howard Candler Professor, Department of
Medicine, Emory University School of Medicine.
Eligible participants or
individuals seeking more information about the study can contact Dr.
Matthey Harris at (404) 321-6111, ext. 7234.