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Dr. Shuming Nie
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Brad Kairdolf   Brad Kairdolf

Office: 2014 Woodruff Memorial Research Building
Telephone: 404-712-9079
Fax:   404-727-3567
E-mail:   brad.kairdolf@bme.gatech.edu
Mailing Address:   101 Woodruff Circle, Suite 2007 Atlanta, GA 30322
Web:   www.kairdolf.com

    Education l Research Summary l Publications l Fellowships l Honors & Awards  

Georgia Institute of Technology and Emory University, Atlanta, GA
Doctorate of Philosophy, Biomedical Engineering
Minor: Business
Expected Fall 2008
Dupree College of Management, Georgia Institute of Technology, Atlanta, GA
Technological Innovation: Generating Economic Results (TI:GER) Program
Expected May 2008
Louisiana State University (LSU), Baton Rouge, LA
Bachelor of Science, Biological Engineering (Summa Cum Laude)
Minors: Chemistry; Biology
May 2003
    Research Summary  

The focus of my research interests is in the development and use of nanoparticles for medical imaging or drug delivery applications.  For nanoparticle development, my research is focused on new synthesis procedures for optical (quantum dot) and magnetic (iron oxide) nanoparticles as well as nanoparticle coating and surface engineering to optimally design reagents for ultrasensitive biological assays.  This research has led to the development of quantum dots with “nonstick” surfaces to eliminate the nonspecific binding problems commonly seen in cell and tissue staining while maintaining a much smaller size than comparable nanoparticles with PEG coatings.

For applications development, my research interest is in utilizing these “nonstick” quantum dots for multiplexed staining of cells and tissues for biomarker analysis as well as solution assays for ultrasensitive biomarker detection.  The secondary focus of my research is to utilize these nanoparticles for single molecule tracking in live cells.


Publications and Presentation

Kairdolf BA and Nie SM.  Joint Society of Molecular Imaging: September 9, 2007.

Kim G, Kairdolf BA, Li J and Nie SM.  Cancer Nanotechnology – Designing Multifunctional Nanostructures for Targeting Tumor Cells and Vasculatures.  ACS Meeting: March 26, 2006.

Kim G, Kairdolf BA, Li J, Chen C, Chu L, and Nie SM.  Targeted Cancer Nanotherapeutics.  Emory-Georgia Tech Frontiers of Cancer Nanotechnology Symposium: March 27, 2006.

Rhyner M, Kairdolf BA, Duan H and Nie SM.  Development of Diagnostic and Therapeutic Nanoparticle Agents Using Amphiphilic Polymers.  Emory-Georgia Tech Frontiers of Cancer Nanotechnology Symposium: March 27, 2006.

Kairdolf BA, Monroe WT. Molecular Beacon Sequence Design Algorithm. Proceedings of the 2003 Annual Fall Meeting of the Biomedical Engineering Society: 9.P2.85, 2003.

Kairdolf BA, Whatley J, Maier J.  Design proposal for an automated sterile external mixer. BEST Fellows Day, Louisiana State University Ag Center: May 28, 2003.


NSF IGERT Fellowship (2006-2008)
Center for Drug Design, Development and Delivery Fellowship (2005)
LSU BEST Biotechnology Research Fellowship (2002-2003)

    Honors and Awards  

NSF Fellowship Honorable Mention (2004 and 2005)
Dean’s Medal for Excellence (2003)
University Medalist (2003)
Delivered Valedictory for LSU College of Engineering graduation ceremony (2003)

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