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Summer 2007

 
 
 

 

   
           
         

Graduation recap

Editor's note: The June issue was already in press at the time of the SOM graduation. We wanted to take this opportunity to recap Dr. Lawley's commencement address on May 14, the date of which marked the 35th anniversary of his own graduation from medical school (SUNY-Buffalo). His remarks to the class of 2007 follow.

Welcome to all of you—you, our newest doctors, and to the families and friends who rightly share the sense of accomplishment that permeates this day.
     Graduation is always a milestone for medical school faculty. For four years you have been their life's work, and today they appear to be thinking it was worth every minute. I hope that as you move through your lives, you will make it clear to them, and to your parents, spouses, loved ones, and communities, that you believe in yourself as much as they believe in you.
     This graduation is also a milestone for me. Exactly 35 years ago this month, I was sitting where you are, wishing the graduation speaker would speed it up a bit so I could recite the Hippocratic Oath and begin my life as a real doctor. I must confess that I remember very little about my medical school graduation. I onlyThis year 108 SOM graduates received diplomas, with two receiving MD/PhDs, 11 MD/MPHs, and two MD/MBAs. remember how proud my parents and my wife were and that I couldn't quite believe that I had done it despite the fact that I had never diagnosed a patient or written a prescription completely on my own and yet, I was a doctor—WOW! How did that happen? I knew how little I really knew, how much I needed a lot of supervision, how much I'd forgotten already, and how fast those four years had gone by. I suppose those 35 subsequent years as physician, researcher, and teacher of doctors enables me to look at the class of 2007 with a certain hard-earned wisdom and perspective.
     Let me tell you without exaggeration, you are the most knowledgeable new physicians in history. You have been given knowledge that did not even exist when I was a freshly minted doctor.
     I could speak for hours, but I won't, about the seemingly endless flood of discovery that has changed our view of health and disease over the past 35 years. I will mention two examples. First, the most important, medicine-changing undertaking mankind has ever attempted: the human genome project, the mapping of every gene in the human body as well as that of many of our fellow species. And second, the mapping of every protein produced by those genes, proteins being what actually do the body's work. These new discoveries in genomics and proteomics mean that you, the class of 2007, are among the first physicians to come to professional age with access to the full script of the humanEmory School of Medicine Graduation 2007 instruction book, and they are already changing how we can diagnose, treat, and prevent diseases.
     But perhaps the most important new tools at your disposal are those of the electronic revolution, especially the electronic capture of clinical information and the high-speed analysis of massive amounts of individual data that were unthinkable when I entered medicine. I was in a meeting recently when someone referred to the electronic medical record as the stethoscope of the 21st century. Think about that!
     The electronic medical record allows a physician to pair a patient's entire medical history to the most current scientific and clinical information available. For those of us who began medical practice relying on our own knowledge and experience, it seems an incredible tool. For us, medical decisions had to be based on what we had learned and the experiences of our colleagues. For you, the doctors of tomorrow, medical decisions are and will be evidence-based, diminishing variability among doctors and helping make you master diagnosticians and physicians.
     The real miracle of the electronic medical record is how researchers and epidemiologists can now combine information on millions of patients to see connections that were invisible in smaller numbers. To illustrate, in oncology, decisions about what type of chemotherapy to give an individual are no longer made on a one-size-fits-all basis, but on which drug we can see is most effective for vast scores of patients who have similar disease characteristics, genetics, and prior treatment.
     With this new "stethoscope" of electronic databases and computer access, you, the class of 2007, have incredible power: power to cure patients once considered incurable and power toYears ago, when available technology was only a fraction of what you have today, Albert Schweitzer said we must always take care that our technology does not exceed our humanity. It has never been truer today. understand the causes of diseases only recently hidden in thickets of impenetrable data. As time goes by you will help medicine move forward in ways, and with a velocity, unthinkable only a few years ago.
     But there are two bits of bad news that come with this knowledge and power. The first is that with this amazing technology comes daunting responsibility: issues of privacy and protection of confidential information, certainly, but also the need to assure that technology never replaces the close doctor-patient relationship that has led so many of us to choose and cherish this profession. Years ago, when available technology was only a fraction of what you have today, Albert Schweitzer said we must always take care that our technology does not exceed our humanity. It has never been truer than today.
     Retaining the deep humanity of medicine will be up to you, in the same way that advances of technology are up to you, and I believe your training and experiences at Emory assure that you will never lose sight of that age-old covenant between doctor and patient. Far more than was true for my generation, you have been given a deep appreciation for the complex sociological, psychological, and economic issues surrounding patients, families, and communities. You have gained important insights from diverse communities that Emory serves, especially at Grady Memorial Hospital, and you have been mentored by faculty who understand both medicine and public health. For you, patients have never been—and will never be—"the kidney in bed three." They will never be only some collection of data.
     I said earlier that you are, without exaggeration, the most knowledgeable new physicians in history. Keep in mind that the class of 2008 is going to graduate with even more knowledge, and you are going to have to keep up with them and with each class that follows. William Welch, the great medical educator, said a century ago, "Medical education is not completed at the medical school—it is only begun."
     While at Emory, you learned a lot of stuff. (In memory of some of those late, late nights required to study all that "stuff," let me quote another 20th century medical scholar, Chevalier Jackson, who once said in teaching medical students, the primary requisite is to keep them awake.) Yes, you learned a lot, but even more important, you also learned how to learn and keep learning. Given the explosion of scientific knowledge today, these skills will be more and more critical as time goes by.
     Dr. Francis Collins, the head of the Human Genome Project, is said to have told a graduation audience that "the kind of wisdom conveyed in commencement addresses tends to have a half-life measured in milliseconds." Even so, I am going to conclude by giving you two pieces of advice from my own life.
     First, and this is much harder to do than it sounds, seek out a balanced life. Medicine is a profession so humanly and intellectually interesting and so demanding that it is sometimes hard to turn away from its siren song. But you will be better doctors, as well as better humans, if you develop a balanced life, if you spend time and energy on your family and community, if you learn to appreciate beauty and interests outside of medicine. Listen to the music of life.
     Second, stay open. Some of you knew you were going to be doctors from before you can remember, and some of you believe that when you complete your residency, your life is set forever. But there will be many moments and opportunities in life, in your life, that you can't even imagine now. I thought that I would go to medical school in my hometown of Buffalo, NY, be a resident in some specialty in Buffalo, and then go into private practice in a suburb of Buffalo. I did almost none of those things, and I'm so glad I didn't. I took advantage of opportunities that were presented to me, and I never looked back.
     In medical school, I had virtually no interest in research. After all, I was going to be the ultimate clinician. But when I started training in dermatology at Yale, I began to realize there were soNever forget what brought you to medicine no matter how powerful the technology and science in medicine becomes. Stay true to what you know today: medicine is about taking care of people, not treating diseases. many unanswered questions about disease, and it frustrated me to no end. After my second year of residency, I took a research fellowship at the National Cancer Institute—what I assumed was going to be a slight detour from my set-upon path—and ended up staying at NCI for 13 years. I could not have been happier doing what I was doing, answering some of those unanswered questions and training young scientists. I assumed I would be a researcher my entire professional life and had no interest in administration.
     When I decided to leave the National Institutes of Health and a research-focused life to become chair of dermatology at Emory, most of my research colleagues thought I was crazy—and of course there were days I agreed with them. But academic medicine, first as chair for eight years, then as dean these past 11 years, has been the most exciting adventure I could imagine, one that grows more exciting every year, in large part because of what we now have to offer young doctors-to-be such as yourselves.
     The reason I tell you this story is that I hope you too will remain open to the many options that your own lives will hold. There will be forks in the road, and you should at least pause and try to imagine what would be possible down that path. As Yogi Berra said, "When you reach a fork in the road, take it."
     Some final thoughts:
     Never stop learning. The scientific and medical world is changing even as we sit here today, and in some laboratory or clinical research project something is happening that will change what you learned last week and how you will handle your patients next week.
     Never forget what brought you to medicine, no matter how powerful the technology and science in medicine becomes. Stay true to what you know today: medicine is about taking care of people, not treating diseases.
     Be good to the least fortunate because how you treat them is an indicator of the quality of your character.
     Know this: the happiest people I know in medicine are those who give back every day. They don't drive fancy cars or have big offices, but they have big dreams, and they accomplish them one patient, one student, or one experiment at a time.
     And finally, leave here today knowing that you are among the finest, best prepared doctors for which the world could ask, that you are the kind of doctors the world needs so badly, and that we, your teachers, and now your colleagues, could not be more proud of you.
     Congratulations. Go be great doctors and great human beings. You have what it takes on all counts.

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Fred Sanfilippo to Lead Health Sciences
Dr. Fred SanfilippoMy colleagues and I look forward to working with Fred Sanfilippo, MD, PhD, a transplant immunologist whom Emory University named in late July to lead its own health care enterprise.
     Dr. Sanfilippo will succeed Michael M.E. Johns, MD, as executive vice president for health affairs, CEO of the Woodruff Health Sciences Center, and chairman of the board of Emory Healthcare.
     The appointment is effective October 1, at which time Dr. Johns will assume the position of Chancellor of Emory University.
     Dr. Sanfilippo currently serves as senior vice president and executive dean for health sciences at Ohio State and as CEO of the Ohio State University Medical Center.

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Leadership development in pediatrics
One of the first objectives Dr. Barbara Stoll had in late 2004 as newly minted Chair of the Department of Pediatrics was to get the department's diverse group of physicians, researchers,Dr. Barbara Stoll administrators, and staff together on the same page, whether they work in the Emory Children's Center or elsewhere. "We conducted a survey," says Dr. Lucky Jain, Executive Vice Chair and an MBA graduate from the Goizueta Business School, "and found that faculty and administrators want an environment in which every individual is a leader, there is business and financial training to make their work lives more effective, and patient services are provided with unsurpassed quality." As a result, Dr. Jain launched the Pediatric Executive Program (PEP), an extension of the Woodruff Leadership Academy (created in 2003 by Dr. Michael Johns, CEO of WHSC and soon to be chancellor of the University) to help develop and strengthen individual leadership and foster collegiality and teamwork in the department. In May, PEP's third class had 20 graduates.
     Through monthly weekend workshops and weekly breakfast meetings from January to May each year, participants gain a better understanding of the mission, vision, and strategic plan forDr. Lucky Jain the department, the SOM, the university, and for Children's Healthcare of Atlanta. Department faculty and managers, WHSC and SOM administrators, and Goizueta Business School lecturers provide valuable information on topics such as leadership development, finance, accounting, marketing, development, conflict resolution, and personal and organizational change. Participants have required reading and, this year, prepared two team debates at the end of the course. "One team debated the pros and cons of a stringent conflict of interest policy," says Dr. Jain. "It was moderated by Brenda Seiton [SOM Assistant Dean] and Dr. Claudia Adkison [Executive Associate Dean and a key presenter for PEP]. The second debatecentered on the changes at Hughes Spalding Children's Hospital, which is under new leadership under Children's. We thought this debate would be quite spirited, and it turned out to be one of the most constructive the program has had."
     PEP has encouraged many changes in the department. For example, faculty and staff are paying much more attention to monthly financial and Press Ganey reports, which summarize feedback from patient surveys about clinical services, and have reduced appointment wait times in some of its services. PEP graduates have formed a "PEP Society" and plan to meet regularly after work to keep lines of communication open.

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Psych evaluation
There is no question that the Department of Psychiatry and Behavioral Sciences has made a name for itself over the past decade. "The field has evolved remarkably in recent years," says Dr. Charles Nemeroff, Chair. "Advances in molecular neurobiology, genetics, and functional brain imaging have led to much progress in treating mood disorders." The department has received several major grants and considerable national recognition, such as being the 12th best NIH-funded psychiary department in the nation (with $19.6 million) and being ranked 15th in the country in 2006 by U.S. News & World Report. Other examples include:

The department will enroll 400 patients with major depressive disorder in a new study, which is one of only two Center for Intervention Development and Applied Research (CIDAR) studies funded this year by the National Institute of Mental Health. The Emory CIDAR will explore the predictability of how patients with major depression, who have never been treated before, respond to certain treatments. Doctors currently base their treatments and dosages on cost, convenience, or their own clinical experience. "There are several safe and effective treatments available for depression, but doctors have little to go on in choosing a particular therapy for an individual patient," says Dr. Nemeroff, the CIDAR's principal investigator. Participants will first be evaluated through functional magnetic resonance imaging (fMRI), genetic testing, a stress hormone function test, and a personality assessment before receiving one of three treatments, escitalopram, duloxetine, or cognitive behavior therapy. Three projects within the Emory CIDAR will study the fMRI scans, identify genetic variations of certain genes involved in depression, and evaluate with PET scans the effectiveness of varying doses of antidepressants.
   
Dr. Joseph Cubells, who has a joint appointment in Human Genetics, is lead investigator of a study that explores how a cognitive disorder associated with a missing portion of chromosome 22, known as the 22q11 deletion syndrome (22q11DS), may be related to autism spectrum disorders. The research study is the first of its kind using a combination of the best diagnostic evaluations for autism. Understanding the link between this genetic deletion and autism helps provide an earlier diagnosis and, as a result, more effective treatment. According to Dr. Cubells, "Early treatment is everything. A fundamental property of the brain is that it constantly remodels itself in response to experience. What initially may be a manageable psychiatric or physical problem can eventually become much worse if it is not treated early."
   
The department has received a $2 million endowment from Rex Fuqua, President and CEO, Fuqua Capital Corporation, to create the Rex Fuqua Chair in Child Psychiatry. The gift will establish an endowed chair for the new Emory Childhood and Adolescent Mood Disorders Program. The program will investigate the cause of mood disorders and will establish studies looking into suicide, the third leading cause of death for American children and adolescents. "Emory has a national reputation as a top clinical and research center for adult and late-life mood disorders," says Mr. Fuqua, "so now the need and timing are right to create a center of excellence for child and adolescent mood disorders at Emory." In addition, the estate of his late father, J.B. Fuqua, recently gave $3 million to the Fuqua Center for Late-Life Depression to expand the Center's ongoing effort to extend psychiatric care to older adults in rural Georgia.
   

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New gene research
The NIH has awarded the SOM $3.6 millionto test patients with schizophrenia for a recently discovered variation in the human genome. Dr. Steve Warren, Chair, Human Genetics, is principal investigator.
     While these variations generally do not cause disease on their own, says Dr. Warren, in combination with other genetic changes and/or environmental factors they may contribute to one's overall risk of disease. Using a "DNA chip" technology available to only a few major research centers, the Emory project will screen 500 schizophrenic patients and 500 controls for the variation.

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Meltzer joins American College of Radiology
Carolyn Meltzer was inducted as a fellow in the American College of Radiology at its recent 84th Annual Meeting and Chapter Leadership conference in Washington. She is William P. Timmie Professor and Chair of Radiology and Associate Dean for Research. She also serves as chair of the education committee of the American Society of Neuradiology. The American College of Radiology serves more than 32,000 professionals with programs focusing on the practice of radiology and the delivery of comprehensive health care services.

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New Clinical Trials Directors
Robin GinnThe SOM has appointed Robin Ginn as the new Executive Director and David McLean, Jr. as Associate Director of the Clini-cal Trials Office. This important move will make the SOM's clinical trials process more efficient, centralize operations, and expand the number of trials available to patients.
     Ms. Ginn comes to Emory from Vanderbilt, where she was executive director of research informatics and regulatory affairs. She also has nursing, management, and information systems experience.
     Mr. McLean comes here from St. Joseph's Hospital, where he was the Institutional Review Board Administrator. As an attorney, Mr. McLean will have a particular focus on directing clinical trial pre-awards and providing budget negotiation and Medicare coverage analysis to ensure appropriate billing.

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Thomas J. Lawley, MD
Dean, Emory School of Medicine

   
     
 

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